A New Day for Cataract Surgery


Designed to provide complete confidence in surgical outcomes.

What is an IOL?

An intra-ocular lens (IOL) is an artificial lens implanted in the eye to treat cataracts.


  • Most frequently performed outpatient surgery in the world.
  • Age related cataract is the leading cause of blindness.
  • Excellent surgeons, IOLs and surgical technology deliver great safety outcomes.
  • Patients, however, are frequently left with suboptimal vision because refractive power is difficult to predict.
  • Existing options to modify refractive power are limited, difficult and risky.
  • HARMONI helps surgeons select the right optic the first time with more predictable lens position.
  • HARMONI enables a safe and easy replacement of the optic when required.


The perfect choice for all cataract patients

The HARMONI Modular IOL features a base component and an optic component that work together in elegant simplicity.  The base provides a solid foundation within the capsular bag and enables versatile control by securely receiving the optic component using traditional surgical tools.  Both components of the HARMONI IOL are injected through a micro-invasive clear corneal incision. The versatile design of the Harmoni IOL is intended to incorporate a variety of lens configurations to customize vision to the patients’ needs.

Harmoni Optic


Harmoni Optic


Harmoni Assembled View

Assembled Device




Solid foundation, versatile control

  • Base and optic component work together in elegant simplicity
  • Base component delivers solid foundation within the capsular bag
  • Enhanced stability for a more predictable ELP
  • Easy insertion through a micro-incision
  • Optic component enables versatile control with portfolio of optic configurations and secure connection to base component


Technology for a lifetime

  • Safe and easy replacement of the optic component
  • Portfolio of optics enable vision to be customized to the patients needs
  • One technology platform for all patients



  • Predictable lens position enables enhanced refractive outcomes
  • Safe and easy replacement of the optic component when required
  • Refractive care for a lifetime, no matter what change in lifestyle or pathology a patient encounters
  • Optimize premium IOL patients
    • Easily align the toric meridian without manipulation of the capsular bag
    • Optimize refractive outcomes of a multi-focal IOL
    • Easily address a dissatisfied multi-focal patient with a change of refraction or conversion to monofocal or toric



ClarVista Medical, based in Aliso Viejo, California is a leading developer of innovative products to treat challenging ophthalmic conditions. In 2012 and in conjunction with series A financing, ClarVista was spun out from Prospex Medical, a medical device incubator, to pursue the development of the HARMONI IOL.

Between 2012 and 2014, the company developed the first generation HARMONI system, conducted a thorough first-in-human clinical study and developed a broad portfolio of intellectual property. In 2015, the company closed on a series B financing of $14M which was used to develop the second generation HARMONI system, initiate a larger feasibility clinical trial and obtain CE mark. In 2016, the company completed an interim analysis in its feasibility clinical study, initiated several other clinical studies, and began preparation for a US pivotal IDE study.


Paul McLean

Glenn Sussman

Malik Kahook
MD, Medical Director

Robert E. Atkinson
JD, General & IP Counsel

Paul Yoo
OD, VP of Clinical Affairs


Ali Behbahani, MD
NEA, Partner
Washington, DC

Bob Balch
Cycad Group, Senior Vice President
Santa Barbara, CA

Cynthia Yee
Windham Venture Partners, Principal
New York, NY


Sept. 2016 Stability of modular intraocular lens system and a single-piece hydrophobic acrylic intraocular lens – J of Cataract Refract Surg, Link to article

July 2016 Optic replacement in a novel modular intraocular lens system – Clinical & Experimental Ophthalmology, Link to article

Sep. 2015 Evaluation of stability and capsular bag opacification of a new foldable adjustable intraocular lens – Clinical & Experimental Ophthalmology, Link to article

Jan. 2014 ClarVista-Ophthalmology Times, Download PDF



ClarVista Medical

26800 Aliso Viejo Parkway, Suite 120
Aliso Viejo, CA 92656



ClarVista and HARMONI are registered trademarks of ClarVista Medical, Inc.